Posts Tagged ‘Prostate-specific antigen’
Predicting Success for Prostate Cancer Surgery

- Image by Ian Samuel via Flickr
For senior men who are diagnosed with prostate cancer the decision about deciding to undergo surgery to eradicate the prostate is often a difficult decision for the patient and the doctor. Trying to decide if this type of surgery or other therapy is the best course of action depends in large measure on the probability that the procedure will be curative. If the cancer has already spread beyond the prostate gland, then the surgery will probably not cure the disease. In this case the doctors will not recommend surgery. In many cases the surgeon does not know the extent of the cancer prior to performing the surgery.
Fortunately a newly developed test has been identified that offers hope of revolutionizing the evaluation of cancer prior to deciding on a treatment. This new test measures the circulating tumor cells (CTC) in the bloodstream by both detecting them and allowing a genetic assay of them. The circulating tumor cells are the seeds that allow the cancer to spread or metastasize to other parts of the body. In recent tests patients suffering from prostate cancer who had PSA scores greater than 10 were tested using the CTC test. The ones who tested positive on the CTC test all had potential surgical failure, but those who tested negative on the CTC test showed greater than an 85% chance of a surgical cure.
Latest Word About the PSA Prostate Test?

- Image by programwitch via Flickr
For a number of years men over 50 years of age have been urged by their doctors to get a PSA blood test to help diagnose the condition of their prostate. Very recently the American Cancer Society recommended changing the emphasis from it would be a good idea for men over 50 to get a PSA test to consider the potential risks of treatment before making the decision to get a PSA test to screen for prostate cancer. The reasoning supporting this change of emphasis was based on the trade off between the negative side effects of PSA screening versus the positive benefits of avoiding the test. For example a slightly high PSA blood test may detect prostate cancer, but it can be a false positive. Conversely men with apparently normal PSA scores actually have had cancer, but the test indicated that they did not have cancer. The high PSA score typically was followed by a biopsy and treatments that had negative side effects that included urinary incontinence and impotence.
For these reasons the American Cancer Society made the recommendation that men who do not have special risks of prostate cancer should take counsel with their doctors, in order to reach an informed decision about getting screened for prostate cancer. The American Society of Clinical Oncology, which represents cancer specialists, including those treating prostate cancer patients, is supporting the Cancer Society guidelines. This is good news for senior men who are about to reach the age when they need to be concerned about the health of their prostates.
Get PSA Blood Test for Early Detection

- Image by programwitch via Flickr
Early detection is the key to treating prostate cancer which is the second leading cause of death by cancer among men in America. About 85% of the cases are diagnosed in men between the ages of 55 and 84, so this is of concern for senior men. This result indicates that advancing age is major risk factor for prostate cancer. At the present time the best diagnostic tool for early detection of prostate cancer is the prostate-specific antigen (PSA) blood test combined with the digital rectal exam. The importance of early detection of prostate cancer is confirmed by the reported reduction in the number of deaths by about 8% in 2006 as a result of the early detection of the disease using the PSA test. The good news for senior men is that prostate cancer is nearly 100% survivable if it is detected early.
At this time some advances are being achieved to improve the PSA testing and its interpretation. Several advances include PSA velocity, PSA density the ratio of free to total PSA. These measures can help determine the need for a biopsy. It turns out that a new test for prostate cancer is under development, that is known as the early prostate cancer antigen-2 (EPCA-2) which may be more cancer specific and more accurate. The bottom line for senior men over 50 years of age is that they should have a yearly PSA blood test combined with a digital rectal exam.

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