Posts Tagged ‘Alzheimer’s disease’
Save Your Senior Brains
As we age seniors face the threat of diminished mental capacity that range from some diminished mental capacity to the dreaded Alzheimer disease. These diminishments are linked to changes in senior brains due to aging. Seniors who are concerned about taking preemptive aging steps to protect their brains have a way to take such a preemptive aging step. The good news for seniors is that a single vitamin has a long history of providing support for the aging brains of seniors. The vitamin is commonly called niacinamide which is a type of vitamin B3. Beginning in the 1940s, clinical research into nurturing the brains of seniors led to the discovery that niacinamide removed or improved symptoms such as memory impairment, unwarranted anxiety, and unreasonable annoyance. This is very good good news for seniors who are concerned about fostering their senior health by protecting and nurturing their brains. Preliminary results of using niacinimide with patients suffering from Alzheimer’s disease has shown very good promise in terms of mitigating the effects of that disease in seniors. It appears that the patients who took it in the earlier stages of Alzheimer’s benefited the most.
Another Longevity Gene Activator?

- Image by Anushruti RK via Flickr
The longevity that results from caloric restrictions in diet have been studied for about seventy years. Caloric restrictions really extend longevity in all forms of life. Except for the difficult issue of trying to eat like folks at a monastery, this would be good news for seniors who are concerned about their senior health. It turns out that the folks who research new nutrients have discovered a set of nutrients that can safely stimulate the effects of caloric restriction. These nutrients mimic the the effects of caloric restriction. In addition to the previously known caloric restriction mimetics of resveratrol, pterostilbene, grape seed extracts, quercitin and black tea, researchers have discovered the flavonoid fisetin which is found in strawberries.
The flavonoid fisetin in a somewhat rare nutrient found in very small quantities in plants. In terms of benefiting senior health it is fosters senior health in a least six ways. It maintains healthy levels of the our cells’ internal antioxidant, glutathione. Fisetin is the only polyphenol that induces antioxidant activity with a two-fold benefit, because it protects against cancer and cardiovascular disease. It inhibits glycation in humans that would over the long term can result in Alzheimer’s disease and other types of cognitive deterioration. Among the flavanoids, fisetin holds a very high rank in terms of preventing DNA damage. Fisetin very effectively suppresses inflammatory responses that would otherwise open the door to cancer proliferation. Finally, fisetin provides mitochondrial support to the cells of our bodies and protects them against oxidative stress. This is very good news for seniors who are seeking preemptive aging information to promote their cardiovascular health and avoid cancer, because all of these nutrients are currently available in supplement form.
Spice For Fostering Seniors’ Memory

- Image by iwishmynamewasmarsha via Flickr
This spice has been used medicinally throughout history in China and India. Both its antioxidant and anti-inflammatory effects are well known. The folks in India have used it for centuries as both a spice and food preservative. This spice which is a member of the ginger family is the well known spice with the deep-yellow color called turmeric from which curcumin is derived. Curcumin is a multitalented healthy spice because of its many “anti” properties that include antimicrobial, antitumoral, and anticoagulant to mention just a few. In India the seniors who live in the rural districts have the lowest rates of Alzheimer’s disease in the world which is of particular significance for senior health. Recent medical research in America showed in animal tests that those on diets with curcumin showed large reductions in amyloid and other markers for inflammation of the brain.
At the present time while drugs are being developed to combat Alzheimer’s disease seniors can chose to follow the example of the seniors in rural India and add turmeric to your foods. It will spice up your meals and you might find that you develop a taste for Indian curry and dishes prepared with turmeric. Alternately supplements are available with curcumin extracted from tumeric. The better supplements include bromelain or piperine to assist in absorption of curcumin.
Seniors Need More Vitamin B-12

- Image via Wikipedia
Recent research has identified a serious vitamin B-12 deficiency among many seniors. The researchers estimated that as many as 40% of Americans have low levels of vitamin B-12. Making matters worse some of the drugs used to reduce stomach acid tend to increase the deficiency. In fact more than 20% of seniors over the age of 65 suffer from severe B-12 deficiency. Unfortunately the symptoms of B-12 deficiency may go undetected, because they are subtle. B-12 deficiency has been identified as a link to age-related dementia, cognitive impairment, and depression. Even mild B-12 deficiency may be a contributor to Alzheimer’s disease. Getting adequate B-12 in their diet is obviously a preemptive aging measure that will contribute to senior health.
On the positive side B-12 plays a critical role in breaking down homocystene that contributes heavily to the development of a number of chronic diseases including heart disease, stroke, and rheumatoid arthritis. It turns out that B-12 works synergistically with folic acid to reduce high levels of homocystene. Getting absorption of adequate amounts of B-12 can be a problem for seniors, because of changes in the stomach linings of seniors. This absorption problem means that eating foods that contain B-12 such as meat, milk, and eggs will not help. Taking oral supplements of B-12 may not succeed either, because it is not adequately absorbed. Taking B-12 by injection has its own limitations. Two other approaches offer hope for achieving adequate absorption by seniors. B-12 can be taken sublingually or by one of the newer oral supplements.
Dynamic Duo for Brain Health

- Image via Wikipedia
Maintaining brain health in the senior years is a goal well worth achieving. Of the dreaded diseases that strike seniors the ones that incapacitate the brain are among the most cruel. Among the diseases of the brain, Alzheimer’s disease is one of the worst. Beta-amyloid deposits that cause the buildup of plaque are the precursor of oxidative stress and cell damage that leads to an increased risk for Alzheimer’s. Recent research in the laboratory using a combination of curcumin and vitamin D3 was shown to provide an immune system boost which would protect the brain against beta-amyloid.
The immune system is organized to protect the body against the precursors of diseases so the researchers investigated using either vitamin D3 or curcumin or both in their study for boosting the immune system. One of the tools that the immune system uses to absorb and eject unwanted visitors is the macrophages. In this case vitamin D3 apparently improves the macrophages’ ability to absorb the beta-amyloid. The other half of the dynamic duo, curcumin, apparently improves the macrophages’ ability to hold on to the beta-amyloid until it can eject it. Based on the lab results, the researchers concluded that the combination of curcumin and vitamin D3 may assist the immune system in clearing out the plaque that causes Alzheimer’s.




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