Another Longevity Gene Activator?

Wednesday, June 9, 2010
posted by Gilmore
My first strawberries of this season...
Image by Anushruti RK via Flickr

The longevity that results from caloric restrictions in diet have been studied for about seventy years. Caloric restrictions really extend longevity in all forms of life. Except for the difficult issue of trying to eat like folks at a monastery, this would be good news for seniors who are concerned about their senior health. It turns out that the folks who research new nutrients have discovered a set of nutrients that can safely stimulate the effects of caloric restriction. These nutrients mimic the the effects of caloric restriction. In addition to the previously known caloric restriction mimetics of resveratrol, pterostilbene, grape seed extracts, quercitin and black tea, researchers have discovered the flavonoid fisetin which is found in strawberries.
The flavonoid fisetin in a somewhat rare nutrient found in very small quantities in plants. In terms of benefiting senior health it is fosters senior health in a least six ways. It maintains healthy levels of the our cells’ internal antioxidant, glutathione. Fisetin is the only polyphenol that induces antioxidant activity with a two-fold benefit, because it protects against cancer and cardiovascular disease. It inhibits glycation in humans that would over the long term can result in Alzheimer’s disease and other types of cognitive deterioration. Among the flavanoids, fisetin holds a very high rank in terms of preventing DNA damage. Fisetin very effectively suppresses inflammatory responses that would otherwise open the door to cancer proliferation. Finally, fisetin provides mitochondrial support to the cells of our bodies and protects them against oxidative stress. This is very good news for seniors who are seeking preemptive aging information to promote their cardiovascular health and avoid cancer, because all of these nutrients are currently available in supplement form.

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